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Animal replica scientific tests have not been conducted Using the drug mix-promethazine and codeine. It's not necessarily known whether this drug combination can cause fetal damage when administered to a Expecting girl or can have an impact on copy capacity.

We foresee reposting the pictures when we are in a position discover and filter out photos that don't match the knowledge delivered during the drug labels. NDC Codes

Pediatric patients must be supervised in order to avoid prospective damage in bicycle Using or in other dangerous activities.

Caution must be exercised when promethazine hydrochloride and codeine phosphate syrup is administered to the nursing female.

Codeine has low plasma protein binding with about seven to twenty five% of codeine sure to plasma proteins. Codeine passes the blood brain barrier along with the placental barrier. Small amounts of codeine and its metabolite, morphine, are transferred to human breast milk.

Promethazine Promethazine is usually a phenothiazine by-product, which differs structurally from the antipsychotic phenothiazines with the existence of a branched aspect chain and no ring substitution.

For nausea and vomiting in little ones, the same old dose is 0.five mg for each pound of overall body excess weight, as well as the dose really should be modified to your age and pounds on the affected individual along with the severity in the affliction remaining addressed.

Precise reports to check the motion from the drug on parturition, lactation, and progress of your animal neonate were not completed, but a basic preliminary review in rats indicated no impact on these parameters.

Extended-time period animal experiments haven't been carried out to assess the carcinogenic opportunity of codeine or of promethazine, nor are there other animal or human knowledge about carcinogenicity, mutagenicity, or impairment of fertility Using these agents.

Promethazine: Indicators and signs of overdosage with promethazine HCl range from delicate melancholy from the central anxious process and cardiovascular technique to profound hypotension,

Be certain that individuals have an oral dosing dispenser that measures the right quantity in milliliters. Counsel people regarding how to read more make the most of an oral dosing dispenser and properly measure the oral suspension as prescribed.

Hemodialysis just isn't routinely utilized to enhance the elimination of codeine or promethazine from the body.

Correct evaluation of your affected person, right prescribing practices, periodic re-evaluation of therapy, and suitable dispensing and storage are correct measures that assist to limit abuse of opioid medicine.

The diagnostic evaluation of people using this type of syndrome is sophisticated. In arriving in a prognosis, it is crucial to recognize scenarios where the medical presentation features the two severe health-related disease (e.